Office is sold as a one-time purchase, which means you pay a single, up-front cost to get Office apps for one computer. One-time purchases are available for both PCs and Macs. However, there are no upgrade options, which means if you plan to upgrade to the next major release, you'll have to buy it at full price. Microsoft is a subscription that includes the most collaborative, up-to-date features in one seamless, integrated experience.
You also get extra online storage and cloud-connected features that let you collaborate on files in real time. With a subscription, you'll always have the latest features, fixes, and security updates along with ongoing tech support at no extra cost. You can choose to pay for your subscription on a monthly or yearly basis, and the Microsoft Family plan lets you share your subscription with your family for up to 6 people, and use your apps on multiple PCs, Macs, tablets, and phones.
This means that your Office subscription will automatically be renamed to Microsoft Get everything you love about Office , plus the additional benefits as they are released, all at the same price. No action is needed from your end. Changes will begin starting April 21, See system requirements for compatible versions of your devices, and for other feature requirements. The applications available for Mac users and the specific features included may be different from those available for PC users.
With Microsoft , you can be flexible. With your account, you are not limited to exclusively Mac or exclusively PC, so you can transition across devices. Documents that you have created belong fully to you. Internet access is required to install and activate all the latest releases of apps and services included in all Microsoft subscription plans. Note that if you are an existing subscriber, you do not need to reinstall or purchase another subscription.
For Microsoft plans, Internet access is also needed to manage your subscription account, for example to install Office apps on other PCs or to change billing options. Internet access is also required to access documents stored on OneDrive, unless you install the OneDrive desktop app.
You should also connect to the Internet regularly to keep your version of Microsoft up to date and to benefit from automatic upgrades. If you do not connect to the Internet at least every 31 days, your apps will go into reduced functionality mode, which means that you can view or print your documents but cannot edit the documents or create new ones.
To reactivate your apps, simply reconnect to the Internet. You do not need to be connected to the Internet to use the Office apps, such as Word, Excel, and PowerPoint, because the apps are fully installed on your computer.
If you use any of these services, you already have a Microsoft account that you can use or you can create a new account.
Learn more about a Microsoft account. As part of signing up for a trial or purchasing Microsoft , you will be prompted to sign in with a Microsoft account. Interpretation: The observed decreased probability of disease-related treatment failure in the experimental group is probably indicative of the increased efficacy of preoperative chemotherapy as opposed to adjuvant chemotherapy in this setting.
Therefore, the experimental treatment can be considered as a new standard of care in high-risk locally advanced rectal cancer. Abstract Background: Systemic relapses remain a major problem in locally advanced rectal cancer. Associated data ClinicalTrials. Please try again later. If you continue to have this issue please contact customerservice slackinc.
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